Easy Application
Easily Covers Small & Large Areas
Targeted Relief

This article has been medically reviewed for accuracy
Biofreeze and Biofreeze Professional Gel and Roll-On are different formulations of Biofreeze topical products for muscle and joint pain. While both contain the same active ingredient to provide cooling relief, the main difference between Biofreeze and Biofreeze Professional is the menthol concentration.
Whether you’re a patient or provider, read on for a thorough overview of the differences between Biofreeze and Biofreeze Professional Gel and Roll-On, including the best ways to incorporate each for everyday or professional use.
Feature | Biofreeze | Biofreeze Professional |
Menthol Concentration | 4% menthol | 5% menthol |
Primary Use Case | Everyday aches, home use, post-workout | Clinical settings, physical therapy, intense relief at home |
Availability | Widely available in retail stores | Healthcare providers and select retail locations |
Active Ingredient | Menthol | Menthol |
The key difference is the menthol concentration: Biofreeze Professional Gel contains 5% menthol, while standard Biofreeze Gel has 4%. This higher-strength formula is optimized for clinical use and is available through healthcare providers, as well as select retail locations.
Both formulas share the same active ingredient. But Biofreeze Professional Gel is often used in clinical settings.
Both Biofreeze and Biofreeze Professional contain menthol as the active ingredient. However, the formulations may differ in their inactive ingredients, which can affect factors like scent, texture, and application experience.
Biofreeze provides fast-acting, localized relief for everyday aches and pains like sore muscles, arthritis, or post-workout muscle strains. As a topical product, it penetrates the skin quickly and targets only the area you apply it to—unlike oral painkillers (i.e., oral NSAIDs) which affect the whole body.
Biofreeze is applied directly to the skin and works only where it’s needed. It doesn’t contain NSAIDs or narcotics, which means fewer systemic side effects and no risk of opioid addiction. For more information, explore Biofreeze articles that explain how the formula compares to oral medications.
Biofreeze product availability differs slightly between the everyday and professional lines. For example, Biofreeze Overnight Relief products—with menthol and a lavender scent for bedtime use—are only available in the regular Biofreeze line. Biofreeze Professional, designed for clinical use, is offered in gel, spray, or roll-on formats but does not include Overnight Relief options.
Biofreeze Professional contains 5% menthol. It’s often used during physical therapy sessions and can help enhance in-clinic care. Providers may also offer single-use gel packets so patients can try the product at home before buying a full-size product.
Easy Application
Easily Covers Small & Large Areas
Targeted Relief
Mess-Free Application
Easily Covers Small & Large Areas
Long Lasting
This article has been medically reviewed for accuracy


Easy Application
Easily Covers Small & Large Areas
Targeted Relief
Mess-Free Application
Easily Covers Small & Large Areas
Long Lasting
